i-FACTOR™ Bone Graft Technology Platform

i-FACTOR Peptide Enhanced Bone Graft is the only biologic bone graft that utilizes a synthetic small peptide (P-15) bound to an anorganic bone mineral (ABM). This unique P-15/ABM combination acts as an attachment factor for osteogenic cells.

i-FACTOR Bone Graft, a Peptide Bone Matrix (PBM), creates a new category of bone grafting technology and demonstrates the Cerapedics commitment to developing novel orthobiologics. Dig deeper into i-FACTOR Bone Graft by reviewing what’s been published, the mechanism of action animation, and more.

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i-FACTOR Bone Graft is currently available in the following form:

i-FACTOR Bone Graft Putty: Putty can be delivered via the syringe directly into an allograft ring.

i-FACTOR™ Peptide Enhanced Bone Graft is indicated for use in skeletally mature patients for reconstruction of a degenerated cervical disc at one level from C3-C4 to C6-C7 following single-level discectomy for intractable radiculopathy (arm pain and/or a neurological deficit), with or without neck pain, or myelopathy due to a single-level abnormality localized to the disc space, and corresponding to at least one of the following conditions confirmed by radiographic imaging (CT, MRI, X-rays): herniated nucleus pulposus, spondylosis (defined by the presence of osteophytes), and/or visible loss of disc height as compared to adjacent levels, after failure of at least 6 weeks of conservative treatment. i-FACTOR Peptide Enhanced Bone Graft must be used inside an allograft bone ring and with supplemental anterior plate fixation.

i-FACTOR Bone Graft products are sterilized after packaging (terminally sterilized), can be stored at room temperature and have a three-year shelf life. i-FACTOR Bone Graft is ready to use and thus requires no mixing or other preparation prior to use.


Handling Instructions

  • Remove the syringe cap and dispense i-FACTOR Putty by depressing the syringe plunger.
  • i-FACTOR Putty may be dispensed directly into the allograft ring or into a separate sterile receptacle where it can be transferred using traditional surgical instrumentation or by hand.
  • The central cavity of the allograft should be filled with i-FACTOR Bone Graft.

IMPORTANT: Do not irrigate once implanted.


Size and Ordering Information

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